Friday, November 18, 2011

Patients taking simvastatin 80 mg daily have an increased risk of myopathy compared to patients taking lower doses of this drug or other drugs in the same class. The risk appears to be higher during the first year of treatment, is often the result of interactions with certain medicines, and is frequently associated with a genetic predisposition toward simvastating-related myopathy and lead to Zocor Lawsuit. But what about other side-effects that have been associated with statins? Many people are now looking into a connection between Zocor and erectile dysfunction.
Due to the aggressive backlash of these potentially lethal side-effects of Zocor, not much attention has been paid to sexual dysfunction caused by these drugs. This does not mean that Zocor class action lawsuit cannot be filed by Zocor Lawyer. One of the main issues is that,
many men who use statins are at the age where ED can begin to occur on its own. Proving the link between Zocor and ED can be difficult, depending on the seriousness of the case. In June 2011, the FDA called on U.S. doctors to stop prescribing simvastatin 80mg doses to new patients due to the risk of Zocor side effects at those levels. The FDA indicated that the 80mg Zocor dose has the highest rate of muscle injury of any statin and recommended that it only be used by patients who had already taken 80 mg of simvastatin for at least a year without problems.

In a 2006 study in Spain and France, 75 cases of impotence associated with statins were identified. About 90% of men recovered potency on statin withdrawal and in some cases impotence appeared again on re-challenge. All statins were implicated. Though in most men testosterone metabolism in not affected by statin therapy, there is a clear interference with testosterone biosynthesis in some of the affected men, and clear re-challenge evidence of the problem in others. It looks as if this is a real problem for a small number of men. It is far too early to speculate on mechanisms, but testosterone synthesis needs cholesterol, which statins block and, unfortunately, there are no clear cut ways around that fact. 

No comments:

Post a Comment